ReGenesis s02e12 Episode Script
Lethargica
I have Alzheimer's.
I found this in your desk.
"To Dad.
" "I am taking Mom someplace better.
" "So you can never make her feel bad again.
" Jesus Christ! You're the head guy on that panel.
Advised the government.
Told them that genetically modified fish were safe for human consumption.
That's my boy, Dr.
Sandstrom.
One day he's running in the yard.
Next day, his whole body's paralyzed.
Basically we found a group of kids with muscle development problems.
We're looking into their family histories DNA samples.
Bob, are you saying that something was dumped there? It wasn't an accident.
An accident implies I made a mistake, and I did not make a mistake.
I need you to sign these forms that NorBAC is not legally responsible.
Tell you what, I'll sign those papers as soon as you start doing your job around here.
- And what is that supposed to mean? - That means: figure out why things are going missing.
Find out who's fucking around with my lab equipment.
A National Guard unit in Canton, Ohio was doing a routine endurance course.
These are troops ramping up for Iraq.
Excellent condition.
They all came down with the same symptoms.
Headaches, flu-like symptom, blurred vision, severe muscle pain.
And then there was the psychosis.
Sleepiness, right? - Okay.
- Sleepiness into coma.
- Encephalitis Lethargica? - Highly contagious, over 5 million people got it, no one ever figured it out.
Yes, Sir.
I'll put a note on his desk.
Connor McGuinn's office.
I'm sorry, he's in a meeting.
I'll make sure he gets the message.
Thank you for holding.
I'm sorry, Captain McGuinn is out of the office.
Of course.
Connor McGuinn's office.
Yes, Ms.
Morrison, I'll put you right through.
Connor McGuinn's office.
then you're sure it's Encephalitis Lethargica? Jill and I went back to Ohio yesterday to double check the symptomology.
All the Guardsmen have it: fever.
You know, they can barely stay awake.
Hallucinations.
It's progressing exactly like Lethargica.
And the prognosis? Everything I've read, anything from psychosis to death.
Two million people died during the last outbreak in the 20's.
So, we're looking at a highly contagious virus? Depends on the strain.
Which we haven't figured out yet.
Connor, if there is another outbreak, it could kill millions again.
Well, how did we stop it back in the twenties? We didn't.
We got lucky.
Except for a few isolated cases, it just vectored out and disappeared.
And now it just suddenly comes back? It's a retrovirus! It's something we all have sleeping in our DNA.
Is it possible Could Al-Qaeda have the means to wake it up? There's a lot of dirty scientists out there who'd be willing to make a few extra bucks to help them out.
Captain, Dr.
Henshaw is on "two".
Thank you.
Doctor, I'm conferencing you with David Sandstrom and Caroline Morrison.
Good.
Good.
Dr.
Sandstrom, can you hear me? Yeah, fine.
How'd the Guardsmen react to the Levodopa? Good idea you had there, Doctor, but no - No effect.
- Not at all? We even pushed the dosage to the limit.
Levodopa should have gone right to the symptoms.
Then you could be wrong? Maybe we're not dealing with Lethargica.
- We need you right now.
- You know what, Doctor? I've got to go.
No, it's gotta be Lethargica.
Maybe we're looking at a different strain, - or maybe it's been altered to resist Levodopa.
- Altered? - You mean weaponized? - It'd make the perfect weapon.
Something we've ignored for the better part of a century.
Something we haven't got a clue how to fight.
Good morning.
I'll take this.
From the Sick Kids Hospital.
What did you order? One headache, supersized.
Is that the DNA for the National Guard? No.
For the Newfoundland families.
I thought we were finished with that.
Apparently not.
David, wait.
- What? - What do you want to do? Same thing we always do.
Roll up our sleeves and dig in.
- Hi, Bob.
- Hi, Jill.
Where were you? Honey I'm kind of exhausted.
I overslept.
What are you doing? David and Caroline have been on the phone with Cpt.
McGuinn all morning.
So do you think it's Encephalitis Lethargica? I don't know.
I guess it could be.
Dr.
Constantin von Economo was the first to identify it.
Encephalitis Lethargica.
In 1916.
Okay.
Headache, nausea, fever were followed, often the very next day, by chronic fatigue.
There were similar reports before that.
In Lisbon in 1521, in Italy in 1561, - and in Germany in 1605.
- Really? I didn't know that.
So is this the same thing, or a variant? - Who knows? - Hey! David wants to see you two in the conference room, now.
Thanks, Wes.
Hey, you guys.
Check this out.
David was right about the GMO fish.
Look.
Mayko, this meeting is about the Guardsmen in Ohio.
This'll just take a sec, Wes.
So these arrays, they're all the same as Earl Jordan's son.
The genetic inversions.
The parents are all carriers of the anomaly Look at this.
This person was born in 1999.
Born 1948.
Born 2001.
So, these genetic anomalies have been around long before GMO fish.
So, the fish couldn't have caused the genetic mutation.
No.
And the nuclear rods were dumped in, what, 1950's? So the radiation couldn't have caused any damage either.
I'd suggest you put this away for now.
Come on, Wes.
Caroline knows we're not just-- I believe this meeting his called: The Ohio virus.
Okay.
Everybody up to speed on the Guardsmen? Yes, I briefed them: symptoms, treatment.
- Levodopa didn't work.
- Oh.
We've got medical histories, backgrounds.
Okay, representative difference analysis PCRs right away.
Let's find out what this virus is first.
I have the infected blood from the Guardsmen at my station.
- Get uninfected blood from volunteers in the lab.
- Uninfected? Why? Compare the two.
Healthy and unhealthy DNA.
It'll help us find out what's bad: the disease-causing organism.
So, I guess we pool the Guardsmen blood, run a PCR and see what comes up virus.
I want to do individual tests.
One PCR per vial.
David, if we pool it and run one single PCR it'll be faster.
- Faster is good.
- Yeah, but it's not as accurate.
There may be a different viral load in each soldier.
David's right.
We would run the risk of diluting viruses.
So.
One reaction per vial.
- You're a horrible man.
- Thank you.
Let's get the blood flowing.
This is on the back burner, Caroline.
We're just giving it a little stir.
Okay, so the kids in Newfoundland, this is their genetic family history.
Black circles are female carriers.
Black squares are male carriers.
You traced the disease all the way back to the same mom and dad? Gail and Declan Perry.
They emigrated from Ireland in 1812.
One of them must have been a silent carrier.
It's a classic recessive trait.
- Just like blue eyes.
- Yeah.
Yeah.
Both your parents have to give you the blue gene - if you're going to have blue eyes.
- I talked to a couple of local historians.
And as far as we can tell, the Perry family had twelve healthy kids But some of them had to have been carriers.
And then they moved out all around the Burin Peninsula.
And they spread this recessive gene all over the place like a silent time bomb.
Generations later, people don't know that they're related.
Two silent carriers marry.
And there's a one in four chance that the illness genes meet up and make their child sick.
So all the sick kids have the same great-great-great-grandparents? Hmm, hmm.
And remind me, who was it who said that this genetic anomaly had nothing to do with radiation or genetically modified fish? Yeah, go pat yourself on the ass for me.
Or actually, maybe you should do that after you tell the families what's going on.
Mr.
Sandstrom.
Hang on a sec.
What? Yes.
Oh Should I come over? No, no, no.
Thank you for calling.
Right.
Good work, Mayko.
Hello? What? Do you speak English? Oh, good, thank you.
Listen, could you connect me to the Norwegian Institute of Biological Sciences, please? Matias, is that you? David Sandstrom.
I'm good, thanks, how are you? Good.
Listen.
Encephalitis Lethargica.
Yeah, that's right.
The bodies from the Spitsbergen dig? I'm writing a follow up paper on the Spanish Flu outbreak in Denver we had over here last year.
It's on comparative symptomology and misdiagnosis.
Listen, is there any way I can maybe get a tissue sample? Fantastic.
Thanks, Matias.
No, no, Caroline It's not No it's No, my my father.
He wandered away from the nursing home and they don't know where he is, and I can't Yes.
So, it's kind of Yeah.
No, no, no.
See, if If we can isolate the retrovirus in the Guardsmen's blood, we can compare it to a tissue sample from a frozen coalminer who died of Lethargica in 1928.
That's ri I've already ordered it.
Well, just Have them keep working on it.
Vial by vial, okay? Oh! I gotta go.
I gotta go! Hey Dad.
You forget your way home? Why would I want to remember? Those old people drive me nuts.
Come on.
I'll take you back.
I'll stay, thanks.
Dad, it's pouring out.
I got a coat on.
Would you give them a call and tell them I'm out here enjoying the beautiful weather and I'll come back when I'm ready to lie down and die.
Which is not today.
All right, well I guess I'll just, you know, hang out here with you for a while and Fine.
You have things to do Take me back to the hell hole.
- What do we got? - Well, the doctors in Ohio are not giving us any encouraging news.
Three more soldiers on life support.
Oh, shit.
You finished the PCR? We got a lot of bacterial and megaloviral DNA.
Nothing that would cause the symptoms the Guardsmen have.
- But something strange is going on.
- And that is? Well, we keep getting hits on the same piece of DNA.
It looks harmless, but all the Guardsmen, their bodies are producing the same obscure DNA fragment over and over again.
- Sequence it.
- I'll get right on it.
Caroline? McGuinn's holding on line six.
Thanks.
Hey, Connor.
We're working our tails off here.
The Guardsmen, they're getting better.
What? I mean That's fantastic! We have some researchers at Fort Egan to thank.
They said they sequenced the virus and matched it to Encephalitis Lethargica.
So, David's theory was right.
Lethargica is back.
It would appear.
Anyway, then, they dove into the army's arsenal of drugs, worked 'round the clock and developed a cure.
Wow, that's fantastic news.
Have you connected it to Al-Qaeda? Homeland Security is on it, but the bottom line is, if anyone else gets infected, - we've got it covered.
- Right.
Please pass on my thanks to David and the rest of your team.
- They worked hard on this.
- Thanks, Connor.
They found a cure? Already? How the hell did they do that? Well, I'm sure they had a hundred scientists working on it, right? Caroline, if I had a thousand scientists in a thousand labs, working around the clock it'd still be pretty amazing.
- It is amazing, isn't it? - Yeah.
It's more like bullshit.
It took nine years to come up with a drug that had any kind of effect at all on HIV.
And these guys find a cure for an unknown, - unresearched killer in 48 hours? - Something's going on.
Yeah, the government's fucking around.
Again.
They did it with LSD, they did it with mustard gas.
They're trying shit out on their own soldiers.
Okay, how do we prove it? - Get the sequence of viral RNA.
- I'll try.
Oh, and get the names of the guys who worked on the cure.
I mean, if they're that good, maybe they should be working for NorBAC.
- Good night.
- Good night.
- So they are getting better? - It's amazing.
Whatever we injected them with worked like a charm.
Wait a minute.
You don't know what you treated them with? They gave me a vial of something called RV-721.
Then they gave me orders to inject it into all the Guardsmen.
- They ordered you.
- Yeah, I know.
It reeks of human experimentation.
That's why I kept a sample of it.
You've got the cure? I do indeed.
I just don't know what it was we did cure.
I would really love to take a look at what's in that vial.
Can you get up here? I'm just as interested in this as you are, Doctor.
- I can be up there tomorrow.
- Great.
I'll see you then.
Matias, David Sandstrom.
We're just writing up your hazardous transfer protocol.
Oh, great.
That's great.
Listen Who did you send the tissue sample to in the U.
S? Well What do you mean? Well, you got the name of a lab or researcher? We didn't send a sample to anyone in the United States.
Oh, really? I guess they got their sample from someplace else, eh? No.
No.
We have all the samples that exist.
Yeah, that's what I thought.
Okay.
My mistake, my mistake Listen Matias, can you get me that sample sent as soon as possible please.
- Yeah, sure thing.
- Great.
Yes, Bob, I know.
Okay? I know, I know, I just - I want you to keep working on it.
- When does the sample arrive? Right, the tissue sample will be there tomorrow.
- Oh.
Okay.
- Okay.
- Okay.
bye.
- Bye.
Well, I gotta go to Newfoundland to talk to these families.
- Send somebody else, David.
- No, I can't send somebody else, Caroline.
It's personal.
Listen, here's what I want you to do.
I want you to call your friend McGuinn and I want you to ask him how the fuck they were able to identify Encephalitis Lethargica without the only known sample? What? What are you talking about? That's right.
You're telling me they have the only sample in the world? Apparently.
Then that must have been the sample they compared it to.
But you don't know that for a fact.
This is the United States military, Caroline.
We can track down a couple of Martians if we have to.
What's your point? Well in that case can you send me a Martian? You know, the sequenced viral RNA? Sure.
Any particular reason? Well, it's an amazing thing they did.
You know, I think David is a little envious he was beaten to the punch.
He'd like to have a look at it.
You know, scientific curiosity.
- I'll see what I can do.
- Thanks, Connor.
I know many of you have had a long day of traveling, so I'd just like to thank you for all coming today.
Thank you for coming out, Doc.
Basically, your children have a genetic sequence which is reversed.
It's like, instead of A-B-C-D-E, they have E-D-C-B-A.
Okay? Now, this inversion, as we call it, means they can't produce a protein that would allow them to make certain kinds of muscle cells, so without the protein, their muscles become rigid and tense.
Is there a cure? No.
How 'bout making us one? I wish I could.
And I wish it was that easy, I really do, but a cure is years away.
- You got any hope for us, Doc? - Yeah.
This inversion DNA is in all of your genes.
Wait now, if it's in our genes, then my little Hayley might someday stop being normal like my other daughter did? Oh, not necessarily.
See, it's a random combination of recessive We could test her, and then we'd know for sure.
But see, knowing that it's genetic is a really good place to start here.
But if it's genetic, and we gave them them genes, then why don't any of us have it? Well, like I was saying, it's a recessive gene.
So you need the right combination of You need two recessive genes, one from the mother and one from the father in combination to produce the illness.
What if we want to have another child I don't want another baby to suffer they way that our son did.
Okay Hum Here's what we can do.
Early in your pregnancy, we can give you an amniocentesis and we can check for the presence of the gene that stunts the muscle growth.
So so then we abort the babies? Is that it? That's entirely your decision, but The alternative is to treat the fetus in vitro with the missing protein.
The child would never would never get the illness.
Unfortunately, once the child is once the child is born it's too late for the treatment.
I'm going to advise Health Canada that they make this test available to even the farthest outports.
In the meantime It's the results of our research.
Take this home.
Look at it.
Show it to your doctors.
There's a team working on something similar to this in Pennsylvania.
I'll get all our research down to them I appreciate that.
If they don't find nothing, how long's my son got? I'm not really sure.
My best guess would be seven or eight years.
Yeah You know, Dr.
Sandstrom I got caught out in the water one time, in a storm.
I thought it was the end.
But my son is suffering, and the best scientists in the world are powerless to stop it.
I've never been this scared before in my entire life.
I'm sorry, Earl.
Thanks.
For gettin' us the truth.
Good luck.
Wes, has anything come in from McGuinn's office? Not that I know of.
Why? David's expecting some information.
- I'll keep my eye out for it.
- Any word on Dr.
Henshaw? - I haven't heard from him.
- Try to get in touch with him.
I'll get right on that.
Yes, sir.
It's Wes.
Everyone is getting anxious about Henshaw.
What should I tell them? I see.
I will.
Yes, sir.
Yeah, that's the one.
Look, Wes, it's the only number I got for Henshaw, okay? I'm not lying to you so I don't know Call the airlines and find out what flight he booked himself on.
I mean Yeah, good Oh, and Wes, when you're on with the airlines I'm thinking of Christmasing in France this year.
Dad.
You're late.
Shouldn't have given you that extra key.
What are you doing here? What does it look like I'm doing? I'm waiting for you.
Look how beautiful she was.
- Still is.
- Well Fortunately she takes after her Grandad.
Yeah, she's a Sandstrom all right.
Smart, good-looking.
Cranky.
She has your mother's eyes Pretty soon I won't know who she is at all.
And when that day comes, I want you to put a bullet in my head.
I need a beer.
Me too.
- Wes, where's Mayko? - I don't know.
- Jill? - Don't know.
- Bob? - Not the hall monitor.
Really? When did you get demoted? - Hey.
- Hey.
I want to talk to you about those kids.
- Newfoundland kids? - No.
No.
The prion study that you did.
About memory improvement.
The kids in Pennsylvania.
Sure.
How'd it go with the families? Fine, fine.
Really good, actually.
Really good.
Where's Bob? I dunno.
Why do you want to know about the prions? Do you know if he sequenced the Guardsman's DNA yet? - David.
- What? - Prions - Yeah.
Tell me what you know about them.
There were 500 children in the study.
Yeah, I know, but you proved that the prions could improve memory, right? Yeah, anywhere from 25 to 40 points.
- Okay, that might do it.
- David, why are you going back to this? My dad has Alzheimer's.
And I was just kind of thinking that maybe Oh, God.
Your dad.
Jesus, David.
We may have proved they had memory spikes, but those children still aren't going to survive.
I'm just thinking, that maybe - David! - Carlos! Come and see! Could you just put everything together in a box, okay, and put it in my office? All right? - Hey.
- Whatcha got? So Bob sequenced the DNA fragment that kept repeating in the Guardsmen.
- It's a reactivated retrovirus.
- You're absolutely sure? The retrovirus RNA is in the serum of the soldiers.
Blood, not just the cells.
It seems to have come alive and it's moving into the known cell parts of the blood.
I don't believe it, there it is.
All right.
Let's find out if it's infecting the other cells, if it's contagious.
- David? - Yeah.
The frozen tissue from Norway just got here.
Finally! Wow, okay, everybody welcome this coal miner to our lab.
He's going to be helping us out for a little while.
He's got great brains, eh? David, the quality of the sample doesn't look very good.
It's the very best we got, Bob.
So, reverse-amplify the RNA, sequence it.
Anything even close to what we've got out of the Guardsmen - we celebrate.
So I compared the genomes.
This is the Guardsmen, and this is the frozen sample of Lethargica.
- Identical? - 99.
9%! - It's amazing! - You were right, David.
A virus everyone thought was long gone, here it is! We isolated and sequenced Encephalitis Lethargica! It's just too bad somebody else did it first.
David, I'm having a hard time finding Henshaw.
He's a doctor from Ohio on a flight yesterday.
- How fucking hard is that? - I'm doing my best.
I've got a few calls and I just need a little bit more time.
The guy has a cure for Lethargica, Wes.
Just find him.
- I'll get on it.
- Thank you.
Oh shit, Simon.
Oh, okay.
I've had better hellos.
But Oh, all right.
Sorry, I'm just I'm working on this other thing and - I can come back.
- No, no.
Let's get Mayko.
- Mayko.
- What? Oh, holy shit.
Simon! I guess this is your new way of saying hello around here.
When did you get in? Tuesday, last Tuesday I think.
Oh Nice.
Well, to Montreal.
Conference at McGill.
- He's here for 24 hours.
- Oh, to talk about the prions? Yeah.
Come on.
David, it's crazy.
What about How about cognitive enhancers? Gingko Biloba? Come on, Simon.
No listen, there are therapies out there that can help protect the brain against memory impairment.
Not that will make a difference to an Alzheimer's patient.
But we don't know what prions really do, David.
No one does.
It's virgin territory.
Look, this is a fascinating, terrifying idea, but we're not anywhere near ready to go there.
Well, my dad is.
I have absolutely no idea how we would extrapolate from an accidental poisoning over months to a single injection now.
Work with me, Simon.
We'll figure it out.
Okay, supposing we do.
How do we test it? On my dad.
- Right.
I believe that's against the law.
- It is.
I'll take care of that part.
- Yeah, but we'd be accessories.
- What are you? Scientists or lawyers? - Well we're certainly not murderers.
- Yes, okay, yes, he could die.
But, if he doesn't, he'll get a few good, sane years! Which is a hell of a lot better than ten years fucked up with Alzheimer's.
He might die within a month.
Or a week.
You prepared to do that to your father? So, in two hours, you are going to be over the ocean.
I'll be at Heathrow by 8:30.
Back in the lab by nine.
Will that give you enough time en route to ponder the ethics of injecting David's dad with prions.
No.
I think I'm just going to help him figure out how to do that.
Let him worry about the quandary.
Call me.
- I will.
- Good.
And remember, if you change your mind, my lab could always do with a brilliant, beautiful, bioinformatician.
I'll remember.
Bye.
Bye.
Of course, I'll make sure I pass that along.
The two Guardsmen who were unaccounted for, apparently they went on a hiking trip last week.
They still haven't returned.
Okay.
I want to talk to you.
In my office.
Of course.
Caroline, I'm going home.
I'll be on my cell.
David! All the Guardsmen have Lethargica located at 11P43 on the genome.
11P43 has always been a benign piece of junk DNA.
Now it's Lethargica? Yeah, but the good news is it's not contagious, David.
But the '20's strain was extremely contagious.
I think that's the point one percent difference from the frozen sample.
Bob, if it's not contagious how did it spread between 30 Guardsmen? - This is good news? - And the bad news is that we all have Lethargica at 11P43.
What? I checked the blood I took from all of us, ran the DNA.
- We all have it.
- But it's dormant.
It's what's intrinsic in the human genome? Has Jill seen this? I don't know, I haven't seen her.
But David I think you're wrong.
- About what? - The question isn't how it spread.
The question is: What woke it up? You're right.
Or who woke it up.
And are they planning on waking it up in all of us? Shit! Caroline, I'm going home.
I'll be on my cell.
Who'd you call? - When? What call? - Yesterday.
I asked you to follow up on Henshaw.
You made a call.
- Just calling one of my usual sources.
- And who is it? Caroline, what's going on? I don't understand why you're-- Who's your source, Wes? General Coffey.
Who is General Coffey? He's my contact at Homeland Security.
What did he say about Henshaw? He told me that a truck crossed the median and hit him head-on.
And that he's dead.
You led us to believe you were still looking for him.
Why in hell didn't you tell us he was dead? - I was instructed not to.
- Why? I was told that it's a matter of National Security.
Caroline, what would you have done? NorBAC works with Homeland Security, Wes.
Did you tell him that? I'm sorry you were put in that position.
Thank you for understanding.
Go back to work.
Oh.
And Wes if this happens again, you can talk to me.
You got a second for some really bad news? Me first.
Henshaw's dead.
It's been days.
Where are all the samples we asked for? Would you like me to spend a couple hours racing around, tracking them? Come on, Caroline.
I have other things to do.
Like mass-producing your miracle cure, I hope.
What are you talking about? Encephalitis Lethargica is in everybody's DNA, McGuinn.
Yours, mine, the President's.
- So what do you want from me? - Answers Conner.
We need to figure out who's behind this.
And you need to get the antiretroviral to as many vaccine labs as you can, as fast as you can.
And we need to stop whoever found a way to wake Lethargica up.
I told you before, Homeland Security will track down the culprit.
- I'm doing everything I can.
- Bullshit! Why don't you just tell us what's going on! Jill! Hey.
Up here.
You seen Jill? Hi, you've reached Jill.
After the message, leave a beep.
You're not here, you're not there.
Things are going fucking crazy and you're like, AWOL.
Where the hell are you? Call me.
What happened? Her landlord called the lab.
He said he found water coming from under her door.
She's in a coma.
What they say? It's not looking good.
Her GCS is 8.
English, Carlos.
Glasgow Coma Scale.
Eyes are 2, verbal is 2, Motor is 4.
- disappointing.
- What are they trying? Combinations of drugs: D4T, 3TC.
NVP.
I'm going to take some blood and get started working on her.
What's it look like? Jill's blood.
It's deja vu.
now Jill comes down with the same thing.
What the fuck is going on? I need to find out how this retrovirus got reactivated in the Guardsmen.
I need to know what they ate, what they breathed, what they drank, if they were given any medication.
Everything! Yeah.
Yeah, I'll get right on it.
Okay.
Bob.
What made Jill sick? You absolutely sure this fucker isn't contagious? Then give me another explanation.
Look, Jill was in quarantine two weeks ago.
Her stem cells.
I'm going to systematically go through her lab books.
Looking for every possibility.
And the impossibilities, too.
Good, Bob.
- Did you call McGuinn? - I've been calling.
Wes has been calling.
He was supposed to update us today.
- I'm going to Ohio.
- I'll go with you.
- No, you need to stay here.
- Why? Because the lab needs you and Jill needs you.
I don't want you getting into a "head-on with a truck".
I won't, David.
I'll come back with the anti-retroviral.
Good luck.
I was just about to knock.
- What a day! - Yeah, mine's been a real treat too.
What the fuck are you doing here? - Thank you, Connor.
- Don't thank me yet.
The Guardsmen had dramatic recoveries.
Within 24 hours they were walking and talking.
Then they started to get sick again.
Turns out there's a secondary virus, Phase II they're calling it, - and this one's even worse.
- What does it do? All their veins and arteries swell up.
Could it be a reaction to the anti-retroviral? They ruled that out.
Did they put them back on the anti-retroviral? - No effect.
- What are your doctors recommending? So the decision is ours? I'm sorry.
I don't know what to tell you.
If this doesn't work then Jill's dead.
Room 217 code blue.
217.
Jill? No pulse.
Starting CPR.
One, 2, 3, 4, 5.
One, 2, 3, 4, 5.
- Get the atropine, 1 milligram push.
- 1 milligram.
- One, 2, 3, 4, 5.
- Atropine's in.
One, 2, 3, 4, 5.
Atropine's in.
One, 2, 3, 4, 5.
Charge it to 200 joules.
Clear.
Clear.
- 360.
- 360.
Clear.
Dans le prochain épisode : * Jill's lab books.
The retrovirus that she sequenced in her stem cells, is Lethargica.
Same as the Guardsmen.
- That's a hell of a coincidence.
- That's no coincidence.
I got 12,000 sick troops.
In a few minutes I have to make a recommendation to the President.
I need to know if NorBAC is anywhere near a cure.
- No.
- Within a week? We're doing everything we can, Connor.
What is it David! Lethargica retrovirus in the human genome, where is it again? - Fuck.
- What? - That's Jill's handwriting.
- I know, Bob.
It's what she copied down from the Manford brothers' board in Chicago, look! I need a copy of everything that's on Wes' computer.
Is anything wrong? I don't know.
Something occurred to me in New York.
Which is When we talk or even when I just see you at work.
It's like everything I need.
You just wake up, now, okay? I've got a hunch I'd like to follow up.
I'll be sending out this week's mission to all field agents online, and I don't think I can trust anyone else with it.
Remember, only you know the whole story.
Report to regenesistv.
com.
I found this in your desk.
"To Dad.
" "I am taking Mom someplace better.
" "So you can never make her feel bad again.
" Jesus Christ! You're the head guy on that panel.
Advised the government.
Told them that genetically modified fish were safe for human consumption.
That's my boy, Dr.
Sandstrom.
One day he's running in the yard.
Next day, his whole body's paralyzed.
Basically we found a group of kids with muscle development problems.
We're looking into their family histories DNA samples.
Bob, are you saying that something was dumped there? It wasn't an accident.
An accident implies I made a mistake, and I did not make a mistake.
I need you to sign these forms that NorBAC is not legally responsible.
Tell you what, I'll sign those papers as soon as you start doing your job around here.
- And what is that supposed to mean? - That means: figure out why things are going missing.
Find out who's fucking around with my lab equipment.
A National Guard unit in Canton, Ohio was doing a routine endurance course.
These are troops ramping up for Iraq.
Excellent condition.
They all came down with the same symptoms.
Headaches, flu-like symptom, blurred vision, severe muscle pain.
And then there was the psychosis.
Sleepiness, right? - Okay.
- Sleepiness into coma.
- Encephalitis Lethargica? - Highly contagious, over 5 million people got it, no one ever figured it out.
Yes, Sir.
I'll put a note on his desk.
Connor McGuinn's office.
I'm sorry, he's in a meeting.
I'll make sure he gets the message.
Thank you for holding.
I'm sorry, Captain McGuinn is out of the office.
Of course.
Connor McGuinn's office.
Yes, Ms.
Morrison, I'll put you right through.
Connor McGuinn's office.
then you're sure it's Encephalitis Lethargica? Jill and I went back to Ohio yesterday to double check the symptomology.
All the Guardsmen have it: fever.
You know, they can barely stay awake.
Hallucinations.
It's progressing exactly like Lethargica.
And the prognosis? Everything I've read, anything from psychosis to death.
Two million people died during the last outbreak in the 20's.
So, we're looking at a highly contagious virus? Depends on the strain.
Which we haven't figured out yet.
Connor, if there is another outbreak, it could kill millions again.
Well, how did we stop it back in the twenties? We didn't.
We got lucky.
Except for a few isolated cases, it just vectored out and disappeared.
And now it just suddenly comes back? It's a retrovirus! It's something we all have sleeping in our DNA.
Is it possible Could Al-Qaeda have the means to wake it up? There's a lot of dirty scientists out there who'd be willing to make a few extra bucks to help them out.
Captain, Dr.
Henshaw is on "two".
Thank you.
Doctor, I'm conferencing you with David Sandstrom and Caroline Morrison.
Good.
Good.
Dr.
Sandstrom, can you hear me? Yeah, fine.
How'd the Guardsmen react to the Levodopa? Good idea you had there, Doctor, but no - No effect.
- Not at all? We even pushed the dosage to the limit.
Levodopa should have gone right to the symptoms.
Then you could be wrong? Maybe we're not dealing with Lethargica.
- We need you right now.
- You know what, Doctor? I've got to go.
No, it's gotta be Lethargica.
Maybe we're looking at a different strain, - or maybe it's been altered to resist Levodopa.
- Altered? - You mean weaponized? - It'd make the perfect weapon.
Something we've ignored for the better part of a century.
Something we haven't got a clue how to fight.
Good morning.
I'll take this.
From the Sick Kids Hospital.
What did you order? One headache, supersized.
Is that the DNA for the National Guard? No.
For the Newfoundland families.
I thought we were finished with that.
Apparently not.
David, wait.
- What? - What do you want to do? Same thing we always do.
Roll up our sleeves and dig in.
- Hi, Bob.
- Hi, Jill.
Where were you? Honey I'm kind of exhausted.
I overslept.
What are you doing? David and Caroline have been on the phone with Cpt.
McGuinn all morning.
So do you think it's Encephalitis Lethargica? I don't know.
I guess it could be.
Dr.
Constantin von Economo was the first to identify it.
Encephalitis Lethargica.
In 1916.
Okay.
Headache, nausea, fever were followed, often the very next day, by chronic fatigue.
There were similar reports before that.
In Lisbon in 1521, in Italy in 1561, - and in Germany in 1605.
- Really? I didn't know that.
So is this the same thing, or a variant? - Who knows? - Hey! David wants to see you two in the conference room, now.
Thanks, Wes.
Hey, you guys.
Check this out.
David was right about the GMO fish.
Look.
Mayko, this meeting is about the Guardsmen in Ohio.
This'll just take a sec, Wes.
So these arrays, they're all the same as Earl Jordan's son.
The genetic inversions.
The parents are all carriers of the anomaly Look at this.
This person was born in 1999.
Born 1948.
Born 2001.
So, these genetic anomalies have been around long before GMO fish.
So, the fish couldn't have caused the genetic mutation.
No.
And the nuclear rods were dumped in, what, 1950's? So the radiation couldn't have caused any damage either.
I'd suggest you put this away for now.
Come on, Wes.
Caroline knows we're not just-- I believe this meeting his called: The Ohio virus.
Okay.
Everybody up to speed on the Guardsmen? Yes, I briefed them: symptoms, treatment.
- Levodopa didn't work.
- Oh.
We've got medical histories, backgrounds.
Okay, representative difference analysis PCRs right away.
Let's find out what this virus is first.
I have the infected blood from the Guardsmen at my station.
- Get uninfected blood from volunteers in the lab.
- Uninfected? Why? Compare the two.
Healthy and unhealthy DNA.
It'll help us find out what's bad: the disease-causing organism.
So, I guess we pool the Guardsmen blood, run a PCR and see what comes up virus.
I want to do individual tests.
One PCR per vial.
David, if we pool it and run one single PCR it'll be faster.
- Faster is good.
- Yeah, but it's not as accurate.
There may be a different viral load in each soldier.
David's right.
We would run the risk of diluting viruses.
So.
One reaction per vial.
- You're a horrible man.
- Thank you.
Let's get the blood flowing.
This is on the back burner, Caroline.
We're just giving it a little stir.
Okay, so the kids in Newfoundland, this is their genetic family history.
Black circles are female carriers.
Black squares are male carriers.
You traced the disease all the way back to the same mom and dad? Gail and Declan Perry.
They emigrated from Ireland in 1812.
One of them must have been a silent carrier.
It's a classic recessive trait.
- Just like blue eyes.
- Yeah.
Yeah.
Both your parents have to give you the blue gene - if you're going to have blue eyes.
- I talked to a couple of local historians.
And as far as we can tell, the Perry family had twelve healthy kids But some of them had to have been carriers.
And then they moved out all around the Burin Peninsula.
And they spread this recessive gene all over the place like a silent time bomb.
Generations later, people don't know that they're related.
Two silent carriers marry.
And there's a one in four chance that the illness genes meet up and make their child sick.
So all the sick kids have the same great-great-great-grandparents? Hmm, hmm.
And remind me, who was it who said that this genetic anomaly had nothing to do with radiation or genetically modified fish? Yeah, go pat yourself on the ass for me.
Or actually, maybe you should do that after you tell the families what's going on.
Mr.
Sandstrom.
Hang on a sec.
What? Yes.
Oh Should I come over? No, no, no.
Thank you for calling.
Right.
Good work, Mayko.
Hello? What? Do you speak English? Oh, good, thank you.
Listen, could you connect me to the Norwegian Institute of Biological Sciences, please? Matias, is that you? David Sandstrom.
I'm good, thanks, how are you? Good.
Listen.
Encephalitis Lethargica.
Yeah, that's right.
The bodies from the Spitsbergen dig? I'm writing a follow up paper on the Spanish Flu outbreak in Denver we had over here last year.
It's on comparative symptomology and misdiagnosis.
Listen, is there any way I can maybe get a tissue sample? Fantastic.
Thanks, Matias.
No, no, Caroline It's not No it's No, my my father.
He wandered away from the nursing home and they don't know where he is, and I can't Yes.
So, it's kind of Yeah.
No, no, no.
See, if If we can isolate the retrovirus in the Guardsmen's blood, we can compare it to a tissue sample from a frozen coalminer who died of Lethargica in 1928.
That's ri I've already ordered it.
Well, just Have them keep working on it.
Vial by vial, okay? Oh! I gotta go.
I gotta go! Hey Dad.
You forget your way home? Why would I want to remember? Those old people drive me nuts.
Come on.
I'll take you back.
I'll stay, thanks.
Dad, it's pouring out.
I got a coat on.
Would you give them a call and tell them I'm out here enjoying the beautiful weather and I'll come back when I'm ready to lie down and die.
Which is not today.
All right, well I guess I'll just, you know, hang out here with you for a while and Fine.
You have things to do Take me back to the hell hole.
- What do we got? - Well, the doctors in Ohio are not giving us any encouraging news.
Three more soldiers on life support.
Oh, shit.
You finished the PCR? We got a lot of bacterial and megaloviral DNA.
Nothing that would cause the symptoms the Guardsmen have.
- But something strange is going on.
- And that is? Well, we keep getting hits on the same piece of DNA.
It looks harmless, but all the Guardsmen, their bodies are producing the same obscure DNA fragment over and over again.
- Sequence it.
- I'll get right on it.
Caroline? McGuinn's holding on line six.
Thanks.
Hey, Connor.
We're working our tails off here.
The Guardsmen, they're getting better.
What? I mean That's fantastic! We have some researchers at Fort Egan to thank.
They said they sequenced the virus and matched it to Encephalitis Lethargica.
So, David's theory was right.
Lethargica is back.
It would appear.
Anyway, then, they dove into the army's arsenal of drugs, worked 'round the clock and developed a cure.
Wow, that's fantastic news.
Have you connected it to Al-Qaeda? Homeland Security is on it, but the bottom line is, if anyone else gets infected, - we've got it covered.
- Right.
Please pass on my thanks to David and the rest of your team.
- They worked hard on this.
- Thanks, Connor.
They found a cure? Already? How the hell did they do that? Well, I'm sure they had a hundred scientists working on it, right? Caroline, if I had a thousand scientists in a thousand labs, working around the clock it'd still be pretty amazing.
- It is amazing, isn't it? - Yeah.
It's more like bullshit.
It took nine years to come up with a drug that had any kind of effect at all on HIV.
And these guys find a cure for an unknown, - unresearched killer in 48 hours? - Something's going on.
Yeah, the government's fucking around.
Again.
They did it with LSD, they did it with mustard gas.
They're trying shit out on their own soldiers.
Okay, how do we prove it? - Get the sequence of viral RNA.
- I'll try.
Oh, and get the names of the guys who worked on the cure.
I mean, if they're that good, maybe they should be working for NorBAC.
- Good night.
- Good night.
- So they are getting better? - It's amazing.
Whatever we injected them with worked like a charm.
Wait a minute.
You don't know what you treated them with? They gave me a vial of something called RV-721.
Then they gave me orders to inject it into all the Guardsmen.
- They ordered you.
- Yeah, I know.
It reeks of human experimentation.
That's why I kept a sample of it.
You've got the cure? I do indeed.
I just don't know what it was we did cure.
I would really love to take a look at what's in that vial.
Can you get up here? I'm just as interested in this as you are, Doctor.
- I can be up there tomorrow.
- Great.
I'll see you then.
Matias, David Sandstrom.
We're just writing up your hazardous transfer protocol.
Oh, great.
That's great.
Listen Who did you send the tissue sample to in the U.
S? Well What do you mean? Well, you got the name of a lab or researcher? We didn't send a sample to anyone in the United States.
Oh, really? I guess they got their sample from someplace else, eh? No.
No.
We have all the samples that exist.
Yeah, that's what I thought.
Okay.
My mistake, my mistake Listen Matias, can you get me that sample sent as soon as possible please.
- Yeah, sure thing.
- Great.
Yes, Bob, I know.
Okay? I know, I know, I just - I want you to keep working on it.
- When does the sample arrive? Right, the tissue sample will be there tomorrow.
- Oh.
Okay.
- Okay.
- Okay.
bye.
- Bye.
Well, I gotta go to Newfoundland to talk to these families.
- Send somebody else, David.
- No, I can't send somebody else, Caroline.
It's personal.
Listen, here's what I want you to do.
I want you to call your friend McGuinn and I want you to ask him how the fuck they were able to identify Encephalitis Lethargica without the only known sample? What? What are you talking about? That's right.
You're telling me they have the only sample in the world? Apparently.
Then that must have been the sample they compared it to.
But you don't know that for a fact.
This is the United States military, Caroline.
We can track down a couple of Martians if we have to.
What's your point? Well in that case can you send me a Martian? You know, the sequenced viral RNA? Sure.
Any particular reason? Well, it's an amazing thing they did.
You know, I think David is a little envious he was beaten to the punch.
He'd like to have a look at it.
You know, scientific curiosity.
- I'll see what I can do.
- Thanks, Connor.
I know many of you have had a long day of traveling, so I'd just like to thank you for all coming today.
Thank you for coming out, Doc.
Basically, your children have a genetic sequence which is reversed.
It's like, instead of A-B-C-D-E, they have E-D-C-B-A.
Okay? Now, this inversion, as we call it, means they can't produce a protein that would allow them to make certain kinds of muscle cells, so without the protein, their muscles become rigid and tense.
Is there a cure? No.
How 'bout making us one? I wish I could.
And I wish it was that easy, I really do, but a cure is years away.
- You got any hope for us, Doc? - Yeah.
This inversion DNA is in all of your genes.
Wait now, if it's in our genes, then my little Hayley might someday stop being normal like my other daughter did? Oh, not necessarily.
See, it's a random combination of recessive We could test her, and then we'd know for sure.
But see, knowing that it's genetic is a really good place to start here.
But if it's genetic, and we gave them them genes, then why don't any of us have it? Well, like I was saying, it's a recessive gene.
So you need the right combination of You need two recessive genes, one from the mother and one from the father in combination to produce the illness.
What if we want to have another child I don't want another baby to suffer they way that our son did.
Okay Hum Here's what we can do.
Early in your pregnancy, we can give you an amniocentesis and we can check for the presence of the gene that stunts the muscle growth.
So so then we abort the babies? Is that it? That's entirely your decision, but The alternative is to treat the fetus in vitro with the missing protein.
The child would never would never get the illness.
Unfortunately, once the child is once the child is born it's too late for the treatment.
I'm going to advise Health Canada that they make this test available to even the farthest outports.
In the meantime It's the results of our research.
Take this home.
Look at it.
Show it to your doctors.
There's a team working on something similar to this in Pennsylvania.
I'll get all our research down to them I appreciate that.
If they don't find nothing, how long's my son got? I'm not really sure.
My best guess would be seven or eight years.
Yeah You know, Dr.
Sandstrom I got caught out in the water one time, in a storm.
I thought it was the end.
But my son is suffering, and the best scientists in the world are powerless to stop it.
I've never been this scared before in my entire life.
I'm sorry, Earl.
Thanks.
For gettin' us the truth.
Good luck.
Wes, has anything come in from McGuinn's office? Not that I know of.
Why? David's expecting some information.
- I'll keep my eye out for it.
- Any word on Dr.
Henshaw? - I haven't heard from him.
- Try to get in touch with him.
I'll get right on that.
Yes, sir.
It's Wes.
Everyone is getting anxious about Henshaw.
What should I tell them? I see.
I will.
Yes, sir.
Yeah, that's the one.
Look, Wes, it's the only number I got for Henshaw, okay? I'm not lying to you so I don't know Call the airlines and find out what flight he booked himself on.
I mean Yeah, good Oh, and Wes, when you're on with the airlines I'm thinking of Christmasing in France this year.
Dad.
You're late.
Shouldn't have given you that extra key.
What are you doing here? What does it look like I'm doing? I'm waiting for you.
Look how beautiful she was.
- Still is.
- Well Fortunately she takes after her Grandad.
Yeah, she's a Sandstrom all right.
Smart, good-looking.
Cranky.
She has your mother's eyes Pretty soon I won't know who she is at all.
And when that day comes, I want you to put a bullet in my head.
I need a beer.
Me too.
- Wes, where's Mayko? - I don't know.
- Jill? - Don't know.
- Bob? - Not the hall monitor.
Really? When did you get demoted? - Hey.
- Hey.
I want to talk to you about those kids.
- Newfoundland kids? - No.
No.
The prion study that you did.
About memory improvement.
The kids in Pennsylvania.
Sure.
How'd it go with the families? Fine, fine.
Really good, actually.
Really good.
Where's Bob? I dunno.
Why do you want to know about the prions? Do you know if he sequenced the Guardsman's DNA yet? - David.
- What? - Prions - Yeah.
Tell me what you know about them.
There were 500 children in the study.
Yeah, I know, but you proved that the prions could improve memory, right? Yeah, anywhere from 25 to 40 points.
- Okay, that might do it.
- David, why are you going back to this? My dad has Alzheimer's.
And I was just kind of thinking that maybe Oh, God.
Your dad.
Jesus, David.
We may have proved they had memory spikes, but those children still aren't going to survive.
I'm just thinking, that maybe - David! - Carlos! Come and see! Could you just put everything together in a box, okay, and put it in my office? All right? - Hey.
- Whatcha got? So Bob sequenced the DNA fragment that kept repeating in the Guardsmen.
- It's a reactivated retrovirus.
- You're absolutely sure? The retrovirus RNA is in the serum of the soldiers.
Blood, not just the cells.
It seems to have come alive and it's moving into the known cell parts of the blood.
I don't believe it, there it is.
All right.
Let's find out if it's infecting the other cells, if it's contagious.
- David? - Yeah.
The frozen tissue from Norway just got here.
Finally! Wow, okay, everybody welcome this coal miner to our lab.
He's going to be helping us out for a little while.
He's got great brains, eh? David, the quality of the sample doesn't look very good.
It's the very best we got, Bob.
So, reverse-amplify the RNA, sequence it.
Anything even close to what we've got out of the Guardsmen - we celebrate.
So I compared the genomes.
This is the Guardsmen, and this is the frozen sample of Lethargica.
- Identical? - 99.
9%! - It's amazing! - You were right, David.
A virus everyone thought was long gone, here it is! We isolated and sequenced Encephalitis Lethargica! It's just too bad somebody else did it first.
David, I'm having a hard time finding Henshaw.
He's a doctor from Ohio on a flight yesterday.
- How fucking hard is that? - I'm doing my best.
I've got a few calls and I just need a little bit more time.
The guy has a cure for Lethargica, Wes.
Just find him.
- I'll get on it.
- Thank you.
Oh shit, Simon.
Oh, okay.
I've had better hellos.
But Oh, all right.
Sorry, I'm just I'm working on this other thing and - I can come back.
- No, no.
Let's get Mayko.
- Mayko.
- What? Oh, holy shit.
Simon! I guess this is your new way of saying hello around here.
When did you get in? Tuesday, last Tuesday I think.
Oh Nice.
Well, to Montreal.
Conference at McGill.
- He's here for 24 hours.
- Oh, to talk about the prions? Yeah.
Come on.
David, it's crazy.
What about How about cognitive enhancers? Gingko Biloba? Come on, Simon.
No listen, there are therapies out there that can help protect the brain against memory impairment.
Not that will make a difference to an Alzheimer's patient.
But we don't know what prions really do, David.
No one does.
It's virgin territory.
Look, this is a fascinating, terrifying idea, but we're not anywhere near ready to go there.
Well, my dad is.
I have absolutely no idea how we would extrapolate from an accidental poisoning over months to a single injection now.
Work with me, Simon.
We'll figure it out.
Okay, supposing we do.
How do we test it? On my dad.
- Right.
I believe that's against the law.
- It is.
I'll take care of that part.
- Yeah, but we'd be accessories.
- What are you? Scientists or lawyers? - Well we're certainly not murderers.
- Yes, okay, yes, he could die.
But, if he doesn't, he'll get a few good, sane years! Which is a hell of a lot better than ten years fucked up with Alzheimer's.
He might die within a month.
Or a week.
You prepared to do that to your father? So, in two hours, you are going to be over the ocean.
I'll be at Heathrow by 8:30.
Back in the lab by nine.
Will that give you enough time en route to ponder the ethics of injecting David's dad with prions.
No.
I think I'm just going to help him figure out how to do that.
Let him worry about the quandary.
Call me.
- I will.
- Good.
And remember, if you change your mind, my lab could always do with a brilliant, beautiful, bioinformatician.
I'll remember.
Bye.
Bye.
Of course, I'll make sure I pass that along.
The two Guardsmen who were unaccounted for, apparently they went on a hiking trip last week.
They still haven't returned.
Okay.
I want to talk to you.
In my office.
Of course.
Caroline, I'm going home.
I'll be on my cell.
David! All the Guardsmen have Lethargica located at 11P43 on the genome.
11P43 has always been a benign piece of junk DNA.
Now it's Lethargica? Yeah, but the good news is it's not contagious, David.
But the '20's strain was extremely contagious.
I think that's the point one percent difference from the frozen sample.
Bob, if it's not contagious how did it spread between 30 Guardsmen? - This is good news? - And the bad news is that we all have Lethargica at 11P43.
What? I checked the blood I took from all of us, ran the DNA.
- We all have it.
- But it's dormant.
It's what's intrinsic in the human genome? Has Jill seen this? I don't know, I haven't seen her.
But David I think you're wrong.
- About what? - The question isn't how it spread.
The question is: What woke it up? You're right.
Or who woke it up.
And are they planning on waking it up in all of us? Shit! Caroline, I'm going home.
I'll be on my cell.
Who'd you call? - When? What call? - Yesterday.
I asked you to follow up on Henshaw.
You made a call.
- Just calling one of my usual sources.
- And who is it? Caroline, what's going on? I don't understand why you're-- Who's your source, Wes? General Coffey.
Who is General Coffey? He's my contact at Homeland Security.
What did he say about Henshaw? He told me that a truck crossed the median and hit him head-on.
And that he's dead.
You led us to believe you were still looking for him.
Why in hell didn't you tell us he was dead? - I was instructed not to.
- Why? I was told that it's a matter of National Security.
Caroline, what would you have done? NorBAC works with Homeland Security, Wes.
Did you tell him that? I'm sorry you were put in that position.
Thank you for understanding.
Go back to work.
Oh.
And Wes if this happens again, you can talk to me.
You got a second for some really bad news? Me first.
Henshaw's dead.
It's been days.
Where are all the samples we asked for? Would you like me to spend a couple hours racing around, tracking them? Come on, Caroline.
I have other things to do.
Like mass-producing your miracle cure, I hope.
What are you talking about? Encephalitis Lethargica is in everybody's DNA, McGuinn.
Yours, mine, the President's.
- So what do you want from me? - Answers Conner.
We need to figure out who's behind this.
And you need to get the antiretroviral to as many vaccine labs as you can, as fast as you can.
And we need to stop whoever found a way to wake Lethargica up.
I told you before, Homeland Security will track down the culprit.
- I'm doing everything I can.
- Bullshit! Why don't you just tell us what's going on! Jill! Hey.
Up here.
You seen Jill? Hi, you've reached Jill.
After the message, leave a beep.
You're not here, you're not there.
Things are going fucking crazy and you're like, AWOL.
Where the hell are you? Call me.
What happened? Her landlord called the lab.
He said he found water coming from under her door.
She's in a coma.
What they say? It's not looking good.
Her GCS is 8.
English, Carlos.
Glasgow Coma Scale.
Eyes are 2, verbal is 2, Motor is 4.
- disappointing.
- What are they trying? Combinations of drugs: D4T, 3TC.
NVP.
I'm going to take some blood and get started working on her.
What's it look like? Jill's blood.
It's deja vu.
now Jill comes down with the same thing.
What the fuck is going on? I need to find out how this retrovirus got reactivated in the Guardsmen.
I need to know what they ate, what they breathed, what they drank, if they were given any medication.
Everything! Yeah.
Yeah, I'll get right on it.
Okay.
Bob.
What made Jill sick? You absolutely sure this fucker isn't contagious? Then give me another explanation.
Look, Jill was in quarantine two weeks ago.
Her stem cells.
I'm going to systematically go through her lab books.
Looking for every possibility.
And the impossibilities, too.
Good, Bob.
- Did you call McGuinn? - I've been calling.
Wes has been calling.
He was supposed to update us today.
- I'm going to Ohio.
- I'll go with you.
- No, you need to stay here.
- Why? Because the lab needs you and Jill needs you.
I don't want you getting into a "head-on with a truck".
I won't, David.
I'll come back with the anti-retroviral.
Good luck.
I was just about to knock.
- What a day! - Yeah, mine's been a real treat too.
What the fuck are you doing here? - Thank you, Connor.
- Don't thank me yet.
The Guardsmen had dramatic recoveries.
Within 24 hours they were walking and talking.
Then they started to get sick again.
Turns out there's a secondary virus, Phase II they're calling it, - and this one's even worse.
- What does it do? All their veins and arteries swell up.
Could it be a reaction to the anti-retroviral? They ruled that out.
Did they put them back on the anti-retroviral? - No effect.
- What are your doctors recommending? So the decision is ours? I'm sorry.
I don't know what to tell you.
If this doesn't work then Jill's dead.
Room 217 code blue.
217.
Jill? No pulse.
Starting CPR.
One, 2, 3, 4, 5.
One, 2, 3, 4, 5.
- Get the atropine, 1 milligram push.
- 1 milligram.
- One, 2, 3, 4, 5.
- Atropine's in.
One, 2, 3, 4, 5.
Atropine's in.
One, 2, 3, 4, 5.
Charge it to 200 joules.
Clear.
Clear.
- 360.
- 360.
Clear.
Dans le prochain épisode : * Jill's lab books.
The retrovirus that she sequenced in her stem cells, is Lethargica.
Same as the Guardsmen.
- That's a hell of a coincidence.
- That's no coincidence.
I got 12,000 sick troops.
In a few minutes I have to make a recommendation to the President.
I need to know if NorBAC is anywhere near a cure.
- No.
- Within a week? We're doing everything we can, Connor.
What is it David! Lethargica retrovirus in the human genome, where is it again? - Fuck.
- What? - That's Jill's handwriting.
- I know, Bob.
It's what she copied down from the Manford brothers' board in Chicago, look! I need a copy of everything that's on Wes' computer.
Is anything wrong? I don't know.
Something occurred to me in New York.
Which is When we talk or even when I just see you at work.
It's like everything I need.
You just wake up, now, okay? I've got a hunch I'd like to follow up.
I'll be sending out this week's mission to all field agents online, and I don't think I can trust anyone else with it.
Remember, only you know the whole story.
Report to regenesistv.
com.